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Coupled with endogenous reactive oxygen species (ROS) generated as by-products of various cellular processes, strict regulation of antioxidants is critical to maintaining a balanced reduction/oxidation (redox) state

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Sequencing was performed on the Illumina platform Novaseq X Plus at the Northwestern University NUSeq sequencing facility core, with a targeted sequencing depth of 20,000 and 25,000 reads per sample acquired for RNA and ATAC profiling, respectively

PUFAs, particularly AA and adrenergic acid, are susceptible to oxidation owing to the weak C-H bonds in their diallyl group (Kagan et al., 2017)