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About this article Cite this article The BLUEPRINT consortium

Such validation efforts not only strengthen the credibility of predictive models but also lay the theoretical groundwork for their clinical application

Interestingly, the growth inhibitory concentrations of 5-3,6,11-trihydroxy-24-methyl-9,11-seco-5a-cholest-7-en-9-one on colon (Caco-2) and breast (MCF-7) cell lines were 0.62 and 2.3 mM, respectively, but no toxicity was recorded against RPE-1 cells at a high concentration of 10 mM