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(PubMed) Baik HW, Russell RM

The carbon dioxide variant caused wound contraction, induced collagen remodeling, activated fibroblast growth factor, and reduced transforming growth factor beta

Although the skin will improve after only one session, it is advised to undergo several Dermapen treatments for further skin rejuvenation

While SCLC is mostly chemosensitive in frontline therapy, the inevitable disease relapse in most patients and the subsequent chemoresistance remain formidable problems leading to very poor overall outcome (Ma and Salgia, 2004)