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It is found naturally in our skin and hair

Quantitative Proteomic Analysis of normal and Degenerated Human Intervertebral Disc

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4.2.3 Dual-substrate-competitive inhibitors Dual-substrate-competitive inhibitors compete with the both substrates (SAM and NAM) for the binding sites in NNMT, thereby increasing inhibitors activity and selectivity (Gao et al., 2021)