glutathione reductase with nadph and Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis: iScience Recycling of Glutathione by Glutathione

The decline in oestrogen appears to remove a layer of protection, which in turn accelerates depletion of this critical molecule, creating a cycle that worsens symptoms

Rossi and Pekkurnaz, 2019)

Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors

The body naturally produces peptides, but synthetic peptides can be used to supplement or enhance certain biological functions

Additionally, because low NAD+ is linked to aging, its decline could contribute to the development of various age-related health concerns, including cardiovascular disease, metabolic disorders, the development of neurodegenerative diseases such as Alzheimers and Parkinsons, and cancer