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Because HepG2 cells possess higher CYPOR activity than primary hepatocytes (Schulz et al

Modifications are important for altering functional groups of the membrane components which, in turn, can alter polymerization characteristics, chemical characteristics, physico-chemical characteristics, bonding propensities, electrostatics, hydrophobicity or hydrophilicity changes, diffusion propensity and resistance to diffusion, elasticity, stability, etc., in the final polymerized membrane

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Shi L, An Y, Wang A, Gao Q, Yang Y