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Glucose6-phosphate dehydrogenase deficiency is one of the most common enzyme defects in humans and it is highly prevalent among populations in malaria-endemic areas of sub-Saharan Africa and the Middle East where approximately up to 7.5% of people are affected (Nkhoma et al., 2009)

To evaluate Dihexas ability to cross the BBB and accumulate in brain regions, rats were fitted with carotid cannulas and infused with a mixture of [H]Dihexa (10 Ci) and [C]inulin (2 Ci), a vascular space marker, in 100 l of isotonic saline

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Oxidative stress, Fe 2+ and lipid accumulation are key factors that contribute to ferroptosis

Nanoemulsions (NEs) Nanoemulsions(NEs) are biphasic dispersions of two immiscible liquids: water-in-oil (W/O) or oil-in-water (O/W) droplets stabilized by amphiphilic surfactants, with long-term kinetic and thermodynamic stability