Yes, IM injections for skin health may help, particularly with Vitamin C injections known for their antioxidant support, which promotes collagen production and skin vitality
Note that these two documented starting doses are worlds apart in size 150 mcg versus 2.5 mg is a roughly 17-fold difference
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Taking all this data together it seems logical or appropriate to conclude that, because IGF1-R has a different signalling pathway that can maintain lipid oxidation in the liver, FFA uptake in muscle, and activates mTORC1 could reactivate IR through tyrosine kinase activity on IRS, thus displacing serine phosphorylation, reinstituting insulin signalling
Avoid rubbing or massaging the area right after the shot