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Results: DKO mice on HFHSD were found to be insulin sensitive compared to WT diet controls

In this study, KD alleviated epilepsy-induced neuronal ferroptosis

Chang X, Yamashita K, Sidransky D

The cGAS-STING pathway is a major cytosolic DNA-sensing pathway, where cGAS detects foreign DNA and synthesizes cyclic GMP-AMP, which then binds to and activates STING