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Results and Discussion: Our analysis showed an expected depletion of peripheral CD38+ B cells following anti-CD38 treatment

Its role is tissue-dependent and should not be reduced to the idea that the enzyme is universally harmful

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The 50 mg per-capsule format mirrors the daily oral dose used in published rodent pharmacology

Clinical safety studies involving approximately 900 participants showed no clinically significant hormonal changes with AOD-9604, consistent with its peripheral, fat-tissue-specific mechanism of action