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Bioinformatics 35 , 40894097 (2019)

6b), and was noticeably absent in circular puncta that mostly represent organelles such as peroxisomes and mitochondria (Fig

Significant accumulation of lipid peroxides is observed in brain regions enriched with A oligomers and in 4-HNE-positive areas of AD patients, indicating direct involvement of A in the ferroptosis pathway (118)

345,346 In gastric cancer cells, DLAT expression is notably upregulated, enhancing oxidative phosphorylation by catalyzing the conversion of pyruvate to acetyl-CoA, thereby supplying energy to tumor cells