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doi: 10.4049/jimmunol.1201061 48 KhaderSABellGKPearlJEFountainJJRangel-MorenoJCilleyGEet al

A cascade of several kinases including receptor-interacting protein kinase (RIPK)-1, RIPK3, and mixed lineage kinase domain-like protein (MLKL) has been identified to play a critical role in the regulation of the necroptotic pathway (Wang X