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The significance of anthocyanins in the prevention and treatment of type 2 diabetes

While glucose itself has not been found to modulate transcriptional DNL activity, one glycolytic metabolite, glucose-6-phosphate (G6P), has been linked to increased FAS and ACC expression 19,20

Pietrangelo, A

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14-3-3 protein binding prevents Nedd4-2 from mediating ENaC ubiquitination 25 , potentially through modulated interactions between structured domains of Nedd4-2 based on recent structural studies conducted with N-terminally truncated Nedd4-2 (lacking the C2 domain) 28,29