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For instance, increased levels of IL-6 can upregulate MCP-1 expression in endothelial cells and macrophages, establishing a positive feedback loop that amplifies the inflammatory response (137)

PLoS One 16, e0252927 (2021), Reactant(s): Human, Abstract HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells: Lee, S., Jo, M., et al

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It is also known to play a role in important physiological processes, such as tissue remodelling, wound healing, and embryonic development (Domen et al

In-depth study and clarification of the pathophysiological mechanism of ferroptosis in related diseases will provide new ideas for discovering potential drug targets and clinical prevention methods