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Importantly, commonly used in vitro BBB models, such as transwell systems and endothelial cell lines including RBE4, bEnd.3, and hCMEC/D3 monolayers, have important limitations, as they may overpredict permeability and do not fully recapitulate key in vivo BBB features, including physiological shear stress and multicellular neurovascular architecture (Katt and Shusta, 2020)

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It is considered by researchers to be one of the most selective secretagogues and is an apparent agonist of the growth hormone/ghrelin secretagogue receptor

I know that there are studies that show that sublingual B12 is as good as B12 injections (7) but my own experience suggests that this is NOT the case

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