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The enhanced autophagy in drug-resistant cells is mainly due to the destruction of mitochondrial function caused by tamoxifen, and drug-resistant cells meet their energy demand through autophagy

Petroff D, Blank V, Newsome PN, ShalimarVoican CS, Thiele M, deLedinghen V, Baumeler S, Chan WK, Perlemuter G, Cardoso AC, Aggarwal S, Sasso M, Eddowes PJ, Allison M, Tsochatzis E, Anstee QM, Sheridan D, Cobbold JF, Naveau S, Lupsor-Platon M, Mueller S, Krag A, Irles-Depe M, Semela D, Wong G, Wong VW, Villela-Nogueira CA, Garg H, Chazouilleres O, Wiegand J, Karlas T

The therapy is generally recommended to fit patients in the second line, especially to ease symptoms or as a bridge to targeted treatments within or outside of clinical trials

doi: 10.1016/j.ajog.2008.07.048 Summary Keywords preeclampsia, nutrient metabolism, pathogenesis, carbohydrate, lipid, amino acids Citation Li S, Zhu J, Zhao Y, An P, Zhao H and Xiong Y (2025) Metabolic disorder of nutrientsan emerging field in the pathogenesis of preeclampsia