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Moreover, alterations in signalling through these pathways leads to a diverse number of diseases including many cancers, neurodevelopmental disorders and metabolic syndromes, highlighting the critical importance of understanding the precise regulation of these pathways and their interconnectivity

consulting fees from AbbVie, Amgen, Bayer AG, Bayer HealthCare Pharmaceuticals, Boehringer Ingelheim, Corcept, Endogenex, Gasherbrum Bio, Genprex, Getz Pharma, Intas Pharmaceuticals, Lilly, Novo Nordisk, Pfizer, Sun Pharmaceutical Industries and Verdiva