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doi: 10.1016/j.ejphar.2008.05.006 [DOI] [PubMed] [Google Scholar] 15.Tenorio M, Graciliano NG, Moura FA, et al

Side Effects: Methylcobalamin is generally well-tolerated, but potential side effects can include: Local reactions at the injection site (mild swelling or irritation) Allergic reactions (rare) Precautions: Monitor animals for any adverse reactions post-injection

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Experiments also confirmed the specific depletion of the ribosome splitting factor ABCE1 and the DNA polymerase subunit POLD1

A decrease in plasma calcitriol and/or a disturbance of its action at the level of the parathyroid cell, which are both frequently observed in uremic patients, may cause disinhibition of c-myc expression and progression into the cell cycle