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GIP receptor activation enhances insulin secretion, improves fat metabolism, and may contribute to central nervous system effects on appetite that go beyond what GLP-1 alone can achieve

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in Frontiers in Endocrinology (2018) suggests this oxidative modification process may contribute to immune recognition and the development of autoimmune thyroid disease, such as Hashimotos thyroiditis and Graves disease (13,13)

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The abnormal cholesterol profile in patients with preclinical RA and early RA is typical of metabolic syndrome: normal or mildly elevated total cholesterol, LDL cholesterol and triglycerides, associated with decreased HDL cholesterol levels (122, 123)