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Genetic variation, including single nucleotide variants, small indels, structural variants, copy number variants and short tandem repeats, is another important cause of PD, which is associated with about 10% of cases (Wang C

13.2% ionomycin

Chelating agents such as deferoxamine and deferasirox can reduce iron availability and may be delivered via inhalation to selectively target iron-laden AMs [149]

(-)-epicatechin, a natural flavonoid compound, protects astrocytes against hemoglobin toxicity via nrf2 and AP-1 signaling pathways

Disruption of the blood-testis barrier disrupts testosterone synthesis, which in turn leads to diminished germ cell adhesion, germ cell death, decreased sperm count, and either subfertility or infertility (4951)