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At the same time, limitations remain obvious: clinical data are still insufficient, most conclusions are based on experimental models, and questions of long-term safety, application protocols, and effectiveness at later stages of degeneration require additional research

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Reported Gamma Glutamyl Activation of Peptide-Bond Synthesis

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Emerging studies (51, 52) indicate the importance of eliminating the upstream stage of the adenosinergic axis by targeting tumor hypoxia and redox state using antihypoxic oxygenation strategies to reinvigorate immunotherapy