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Climacteric 19(6):551552 Gao B, Gao W, Wu Z, Zhou T, Qiu X, Wang X, Lian C, Peng Y et al (2018) Melatonin rescued interleukin 1-impaired chondrogenesis of human mesenchymal stem cells

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In recent years, GHK-Cu has evolved from a dermatological bioactive ingredient into a representative model system linking coordination chemistry, peptide bioactivity, and biomanufacturing engineering

Not only do these compounds solubilize cellular membranes but also integrate cellular signaling pathways

Compared with GHK, its copper (II)-chelated form shows a more prominent antioxidant and anti-inflammatory effect in both in vitro and in vivo studies