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In ferroptosis, SLC7A11 and GSH depletion lead to iron-dependent ROS accumulation ( Ferroptosis and alzheimers disease Iron homeostasis and alzheimers disease Regulation of iron homeostasis is important for maintaining normal brain function, and dysregulation of iron homeostasis in the brain can lead to oxidative stress and inflammatory responses, resulting in cell damage and ultimately neurodegenerative diseases

Knockdown of YTH N(6)-methyladenosine RNA binding protein 2 (YTHDF2) inhibits proliferation and promotes apoptosis in MGC-803 gastric cancer cells]