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This is because vitamin B12 is absorbed by first combining it with a protein called intrinsic factor produced in the stomach, then the B12 has to travel down the small intestine to an area called ileum for it to be absorbed properly

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Minimum and maximum diameter parameters were assigned to identify appropriate cells for the automated adipocyte area calculations, and cells along the boundary of the images were excluded from analyses

If you have low IGF-1, then the most likely cause for your condition is GHD