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Description

1112,1113 In Huntingtons disease, antisense oligonucleotides target mutant HTT mRNA to prevent disruptions in mitochondrial transport and function

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10.1007/s40200-022-01053-9 118 ZhangB.ChenX.RuF.GanY.LiB.XiaW.et al (2021)

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ASD varies in degrees of severity, occurring in 1% of the population, and its prevalence has been increasing during the last three decades ( FMR1 gene sequence on the chromosome X that results in fragile X syndrome (FXS) or fragile X-premutation tremor/ataxia syndrome (FXTAS) are among the leading genetic causes of ASD ( It has been recently proposed that a significant number of ASD cases could be associated with various metabolic abnormalities, some of them identifiable only through untargeted metabolomic profiling, simultaneously opening additional space for therapeutic attempts ( Inborn Errors of Metabolism Clinical symptoms deriving from central nervous system (CNS) occur in more than 50% of patients with inborn errors of metabolism (IEM)

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The result can be a rapid shedding of hair on the scalp but also over the entire body

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