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During the MASLD-induced mitochondrial dysfunction, the microsomal CYP2E1- and CYP4-mediated -hydroxylation of FFAs is markedly increased (Daly 2013

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PSSG can modulate the activity and function of various classes of redox-sensitive proteins, such as protein tyrosine phosphatases 1 , metabolic enzymes 2 , and other oxidoreductases 3,4 , and therefore has emerged as a regulatory process with the potential to impact diverse (patho)biological pathways

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This is a set of guidelines from an international group of dermatologists with graded recommendations for systemic treatments of psoriasis