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Currently, therapeutic options for metastatic bladder cancer remain limited, highlighting the urgent need for novel treatment strategies and a better understanding of the molecular mechanisms underlying this disease 5,6,7

At baseline, GRMET, TYRMET, and KYNURIC partial correlations were most impacted, while at week 8, KYNHVA, KYN3OHKY, 5HTP-G, and HGAGR values were most impacted by HRSD 17 week 8 status (Fig