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Caf-au-lait macule extra information Synonyms: CALM, Circumscribed caf-au-lait hypermelanosis, Recklinghausen spot, Caf-au-lait spot, Circumscribed hypermelanosis, cafe au lait, cafe-au-lait Categories: Lesions (benign) ICD-10: L81.3, Q85.0, Q78.1 ICD-11: LC1Y, LD2F.1Y, EC23.1, EC23.0, LD2D.10, LD20.11, FB80.0, LD27.5 SNOMED CT: 201281002, 403816002, 726029005, 703541007, 111306001, 403820003, 15069006 Lesions (benign) Author: Made Ananda Krisna, General Practitioner Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas, Indonesia

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doi: 10.3389/fimmu.2026.1847953 Received 05 April 2026 Revised 20 May 2026 Accepted 26 May 2026 Published 10 June 2026 Volume 17 - 2026 Edited by Sheng Chen, Huazhong University of Science and Technology, China Reviewed by Wang Jiabao, Tianjin University of Traditional Chinese Medicine, China Zhen Liu, The Affiliated Hospital of Qingdao University, China Updates Copyright 2026 Yan, Yang, Xiao, Zhang, Xu, Chen, Zeng, Qian, Zhao, Wang, Xie, Li and Xie