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Most studies sources were searched from Chinese databases consisted of small-sample, single-center studies, leading to publication bias and regional selection bias

The interaction between hypoxia and mitochondria through the -ketoglutarate-dependent dioxygenase family suggests that interventions targeting this family could potentially prevent hypoxia-induced damage to mitochondria (Figure 1)

Group 1 was administered distilled water only throughout the study

Briefly, images were converted to 8-bit images and scald to 0.366 microns per pixel (corresponding to 20 magnification on the Leica microscope)

Chemical Peels: Chemical peels use a gentle chemical such as glycolic, salicylic, citric, trichloroacetic (TCA) acid or retinol to exfoliate the skin, improving its texture and colour