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Meanwhile, their downstream molecules, such as eIF2 and GADD153/CHOP, were also elevated, ultimately resulted in apoptosis

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Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain

Mice treated with SSK1 in a bleomycin-induced pulmonary fibrosis model, harbor less senescent cells within the lungs, associated with a downregulation of senescence-associated genes expression and an improvement of mice physical functions as well as survival rate