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The dose is 100200 mg IM, 23 times weekly

It does takes a while close to 3 years for metformin to have any affect on B12 levels

Product Purchase Includes Medication Medical provider consultation Syringes Alcohol Pads Program guide Administration video Administration and Frequency Available in Subcutaneous (SQ) and Intramuscular (IM) Injections Three times weekly As directed by your prescribing provider Contraindications Compounded Methylcobalamin injections should not be used in individuals who: Have a known hypersensitivity or allergy to cyanocobalamin, methylcobalamin, cobalt, or any component of the formulation Have Leber's disease (hereditary optic nerve atrophy) B12 administration may cause rapid optic atrophy in these patients Have polycythemia vera B12 may accelerate red blood cell production in ways that may be harmful in this condition Use during pregnancy or breastfeeding should occur only if a licensed healthcare provider determines that potential benefits outweigh potential risks

Use the compounded tirzepatide dosage calculator to plan a gradual escalation schedule

Vitamin B12 deficiency symptoms can appear when vitamin B12 levels drop below 200 pg/mL, but some people feel effects even in the low-normal range