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N-acetyl-L-cysteine (NAC), a well-characterized thiol antioxidant and precursor of reduced glutathione (GSH), not only scavenges intracellular ROS directly but also replenishes depleted GSH stores in erythrocytes, thereby inhibiting ROS-mediated Ca 2+ influx and PS externalization induced by eryptosis triggers such as desipramine or uremic toxins

31 , e50 (2022)

Medications : Acetaminophen (Tylenol) is notorious for depleting glutathione

3.8 Site-specific accumulation of GO@GSH-FA in cerebral ischemic regions In the present study, Rhodamine B was employed as a fluorescent marker to track the biodistribution of GO@GSH-FA nanoparticles in C57 mice following intravenous administration

The previously obtained suspension was resuspended in 1% BSA-PBS and then counted using the Countess II Automated Cell Counter