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21 Although the media commonly describes it as a recent phenomenon, fentanyl has been used as a contaminant in illicit drug supplies since at least 1979

Shyamali Dharmage who provided guidance for interpretation of the included studies and provided comments on the manuscript

For instance, overexpression of -syn increases the levels of monounsaturated fatty acids, altering the membrane lipid balance and exacerbating toxicity (139)