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These studies suggest that deficiencies in GH and IGF-I contribute to a functional decline in senescent rats, whereas augmentation of GH or IGF-I improves cognitive function, increases glucose utilization throughout the brain, increases cortical vascularity, and ameliorates age-related decline in hippocampal neurogenesis

further identified seven tear fluid proteins with significantly altered expression, that had a role in protein repair and clearance system or regulation of the cytoskeleton 20

sermorelin : Ipamorelin has a shorter half-life compared to sermorelin but can promote a more significant increase in growth hormone levels without affecting cortisol production

For each sample, 10 ng of total RNA was used to synthesize cDNA with Quantiscript reverse transcriptase from the QuantiTect Reverse Transcription Kit (QIAGEN, Hilden, Germany)

Govender T, Naicker T