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(2010) and Al-Dean and Hammoud (2024) reported that low concentrations of NAC improved motility parameters, while higher concentrations (2.5 and 5 mM) induced hyperactivated motility, potentially leading to premature acrosomal reaction and compromised fertility (Alahmar, 2019)

To validate the methods feasibility, we selected the marketed covalent inhibitors afatinib (for lung cancer) and ibrutinib (for lymphoma) as test compounds, assessing their binding ability to GSH using this approach

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For the AOD-9604 deep dive, see What Is AOD-9604

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