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Description

Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis

Moreover, loss of hepatic PSAT1 impaired glucose tolerance in mice fed the SAAR diet and abolished the increase in liver serine sourced from circulating glucose without completely preventing the rise in liver serine levels

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This results in the accumulation of apoptotic cells, triggering secondary necrosis and further lung damage

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