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Consequently, mtDNA bound to cGAS and activated the downstream signaling that mimicked the functions of macrophages from RA patients, contributing to the pathogenesis of RA (57)

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Structure and molecular architecture of tight junctions Tight junctions (TJs) are dynamic structures, which are formed by the aggregation of an assortment of specific proteins at the apical membrane

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In mouse models, topical application stimulated the formation of entirely new hair follicles, a process called neogenesis