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An additional study on the efficacy of Kojic Acid published in the Journal of Dermatologic Surgery suggested that Kojic Acid is highly effective in reducing the pigment in melasma patients and should be a primary tool used by dermatologists for skin discoloration

This can be due to life stage, malabsorption, or due to genetics

[71] reported that ferroptosis occurs in APAP-induced hepatic injury, showing that ferroptosis inhibitors such as ferrostatin-1 (Fer-1) provided moderate protection against APAP-induced death in primary mouse hepatocytes

The GSH:GSSG ratio may be used as a marker of oxidative stress, which arises due to various malignancies

Mitochondrial dysfunction, impaired axonal transport, and neuroinflammation are key contributors to oxidative stress in ALS [169]