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In the intervention group, it became more positive, i.e., more oxidizing

produced gold nanoparticles (GNP) coated with thiolates that were highly solubilized in water

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05 Related assay kits and supporting reagents Table 1

In this situation, theoretically, there would be insufficient intra-mitochondrial reduced equivalents, which would be consumed by the excess of unquenched ROS produced during the 2D3D transition