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Limit test studies failed to establish an LD50, indicating exceptionally low acute toxicity even at very high doses

Immunomodulatory nanoparticles (IMPs) are highly negatively charged, 500 nm-diameter particles composed of the biodegradable biopolymer carboxylated poly(lactic-co-glycolic) acid (PLGA-COOH) (Sharma et al., 2020

This suggests that the effects of MG extend beyond binding to GSH and involve the inhibition of GSH resynthesis and enzymes that play key roles in its synthesis, thereby promoting ferroptosis

Timing & therapeutic window Ferroptotic cell death in acute cardiac injury occurs within a narrow time frame, making the timing of intervention critical

uralensis under the S condition and the increased fructose content in G