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USSR Comput

doi: 10.1111/bph.12369 10 Turbat-HerreraEAKilpatrickMJChenJMeramATCotelingamJGhaliGet al

Specifically, under stress conditions, JNK/p38 MAPK phosphorylates ATF2 to enhance its transcriptional activity (107), while ER stress activates ATF4 and ATF6 via the unfolded protein response (UPR) to restore proteostasis (106,108)