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A clear association between HHcy and ER stress, where an elevation in variant ER stress markers in adipose tissue of homocysteinemic mice has been demonstrated [97]

Studies of the von Willebrand factor and fibrinogen (important vascular determinants of increased platelet aggregation and secretion that may be involved in the development of thrombosis) also favor the theory of platelet hyperactivity

Lillig et al., 2005)