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Immune hemolytic anemia Result of an immune event that occurs on the surface of the erythrocyte Direct: Action of an antibody on the membrane with or without complement Indirect: an immune complex that is adsorbed on the erythrocyte and fixes complement, which is generated by its lysis by the action of macrophages Autoimmune hemolytic anemia Autoantibodies The direct antiglobulin test, better known as direct Coombs, demonstrates the presence of antibodies or complement on the surface of the red blood cell and is a cornerstone in the diagnosis of autoimmune hemolytic anemia

doi: 10.1186/1471-2172-9-68 159 YadavR.PuniyaA

Stearns EL, MacDonnell JA, Kaufman BJ, Padua R, Lucman TS, Winter JS, et al

While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

High In Vivo Rates of Methionine Biosynthesis in Transformed Human and Malignant Rat Cells Auxotrophic for Methionine