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CYP1A1: Detoxifying Cigarette Smoke and Estrogen Genetic Lifehacks Smoking cigarettes affects many aspects of your body, including your physical endurance. If you smoke, you get less oxygen in your heart, lungs and muscles. This reduces your physical fitness level. Metabolic effects of smoking cessation Nature Reviews Endocrinology Cigarette Smoking, Nicotine, and Body Weight PMC Smoking does not just impact your lungs. It alters your internal systems in ways that are often overlooked. The chemicals in cigarette smoke disrupt the balance of your gut microbiome, increase inflammation

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