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The disruption of the stop signals can be caused by genetic, or inherited, defects in the cells DNA , or by external dangers such as radiation or environmental toxins, such as pollutants or chemicals, both of which can cause damage to the cells DNA

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This fact raises two possibilities: 1) AQP7/9 increases arsenic uptake into adipocytes, hepatocytes, and pancreatic -cells, increasing the toxic effects on these cell types