50 cigarettes a day Researchers at Johns Hopkins University found that even 2–5 raise the risk of cardiovascular disease by almost 50%. Cutting down doesn't help — even “light” or occasional smoking still Quit Smoking Tracker - Time,

[10] THC is converted rapidly to 11-hydroxy-THC, which is also pharmacologically active, so the euphoria outlasts measurable THC levels in blood

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Many of the chemicals and tar in cigarettes have been found to damage arteries and reduce blood flow

Researchers found some evidence that non-serious adverse effects were more common in people receiving nicotine e-cigarettes compared to behavioral support only or no support, and a low number of unwanted effects, including serious effects, were found in studies comparing nicotine e-cigarettes to nicotine replacement therapy