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Importantly, while caloric restriction has been hypothesized to hold preventive effects, malnutritionreported in up to 60% of patients with PDmay complicate this relationship, given its association with adverse health outcomes and poorer quality of life 57

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PMC 4571449

If an NGP delivers nicotine via inhalation, while this will increase the speed of nicotine delivery similar to a combustible cigarette it also incurs more risk than a product thats used orally or dermally