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In particular, it has been proposed that CSF biopsy may be used to adapt radiotherapy should LMD not respond to other treatments [95]

K.BarasaL.PerronJ

Concurrently, it functions as an essential cofactor for prolyl hydroxylase and lysyl hydroxylase, enzymes critical for collagen biosynthesis (Nassar et al., 2025)

To test our hypothesis, we first detected GCLC expression and found that when NRF2 was knocked down, the inhibition of GCLC expression by ACTL6A KD was diminished