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Smoking and Heart Disease CardioSmart American College of Cardiology Smoking is the leading cause of heart disease. Every puff raises your blood pressure, damages your blood vessels, and increases the risk of a heart attack. Quit smoking today Getting Serious About Heart Health Society for Women's Health Research Does Smoking Cause High Cholesterol Smoking affects the heart long before symptoms appear. Each cigarette delivers chemicals that enter the bloodstream within seconds, reaching the heart and blood vessels almost immediately. These substances damage the inner lining
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