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This statistically significant shift might be explained by self-selection of heavy smokers out of the high occupational exposure groups because of the bronchial irritation that is caused by the exposure to chloromethyl ethers, or cigarette smoking might have an antagonistic activity (Steenland & Thun, 1986

10.1111/j.1365-2125.2007.02846.x Summary Keywords adverse drug reactions, cytochrome P450, diabetes mellitus, drug-drug interactions, drug metabolism, smoking cessation Citation Bellanca CM, Augello E, Di Benedetto G, Burgaletto C, Cantone AF, Cantarella G, Bernardini R, Polosa R and the DiaSmokeFree Working Group (2024) A web-based scoping review assessing the influence of smoking and smoking cessation on antidiabetic drug meabolism: implications for medication efficacy

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Wendell M Stanley (left) and bottle with a suspension containing paracrystals of TMV, isolated in 1935

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